ORIGINAL PAPER
Concomitant sensitization to glutaraldehyde
and methacrylic monomers among dentists and their patients
More details
Hide details
1
Medical University, Sofia, Bulgaria
(Faculty of Medicine, Department of Hygiene, Medical Ecology and Nutrition)
2
Medical University, Sofia, Bulgaria
(Faculty of Dental Medicine, Department of Oral and Image Diagnostic)
3
Military Medical Academy, Sofia, Bulgaria
(Legal Department)
Corresponding author
Maya Grigorievna Lyapina
Medical University, Faculty of Medicine, Department of Hygiene, Medical Ecology and Nutrition, 15 Boulevard, Academik Ivan Evstatiev Geshov, 1431 Sofia, Bulgaria
Med Pr Work Health Saf. 2016;67(3):311-20
KEYWORDS
TOPICS
ABSTRACT
Background: A multitude of methacrylic monomers is used in dentistry. Glutaraldehyde (G) is used in dental practice and consumer
products as a broad-spectrum antimicrobial agent. The purpose of our study is to evaluate the frequency and the risk
of concomitant sensitization to some methacrylic monomers (methyl methacrylate (MMA), triethyleneglycol dimethacrylate
(TEGDMA), ethyleneglycol dimethacrylate (EGDMA), 2,2-bis-[4-(2-hydroxy-3-methacrylo-xypropoxy)phenyl]-propane (Bis-GMA),
2-hydroxy-ethyl methacrylate (2-HEMA) and tetrahydrofurfuryl methacrylate (THFMA)) and glutaraldehyde in students
of dentistry, students from the dental technician school, dental professionals and dental patients. Material and Methods: A total of 262 participants were included in the study: students of dentistry, students from the dental technician school, dental
professionals, and dental patients as a control group. All were patch-tested with methacrylic monomers and glutaraldehyde. The
results were subject to the statistical analysis (p < 0.05). Results: Among the group of dental students, the highest frequency of
concomitant sensitization was to TEGDMA and G (15.5%). In the group of patients the highest frequency of concomitant sensitization
was to EGDMA and G (16.4%). The frequency of concomitant sensitization among dental professionals was much lower,
with the highest rate to TEGDMA and G (7.7%), too. We consider the students from the dental technician school, where the exposure
to glutaraldehyde is less likely, to be the group at a lesser risk of concomitant sensitization. Conclusions: Dental students and
dental patients could be outlined as groups at the risk of concomitant sensitization to glutaraldehyde and methacrylic monomers.
For dental professionals, we assumed an increased risk for concomitant sensitization to TEGDMA and aldehydes that are commonly
used in dentistry. We consider the students from the dental technician school to be the group at a lesser risk of concomitant
sensitization to glutaraldehyde and methacrylic monomers. Med Pr 2016;67(3):311–320