Introduction: The purpose is to present the incidence of occupational diseases and their causal factors in the sections and divisions of the national economy in Poland. Material and Methods: The analysis is based on the cases of occupational diseases obligatorily reported in 2009-2011 from all over the country to the Central Register of Occupational Diseases. Data is presented as absolute numbers and average annual incidence rates per 100 000 persons employed in NACE-classified sections and divisions. Results: The average annual incidence of occupational diseases was 20.6 cases per 100 000 of employed people. The highest rates were recorded in mining and quarrying (337.8), the production of metals (169.8), non-metallic mineral products (81.6), motor vehicles and transport equipment (59.7), chemicals (30.1). Specific situation in which high incidence rate is due to a single disease prevails in forestry, where tick-borne diseases represent 96.3% of all recorded cases, in education, where chronic voice disorders account for 96.5% of cases, and in human health and social work activities, where infectious diseases with the dominant hepatitis C represent 68.2% of the cases. The most common causes of occupational diseases in sections and industrial divisions with the highest incidence included: industrial dust, noise and vibration. In the manufacturing industry asbestos was the cause of 20.5% of occupational diseases and 55% of occupational cancers. Conclusions: Careful monitoring of working conditions and implementing health prevention programs should be exercised in sections and divisions of the national economy where a high risk of occupational diseases has been found. Med Pr 2013;64(2):161–174